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QuikRead go CRP point-of-care test provides valuable information when evaluating bacteraemia infections in febrile children of less than three months

Retrospective study has been carried out at the West China Second University Hospital Paediatric Emergency Department during the influenza seasons from June 2013 to January 2015. Focus of the study was to explore whether C-reactive protein (CRP) concentrations could indicate which infants with fever without source (FWS) should receive undergo blood culture tests during influenza season.
CRP concentration was measured by the QuikRead go immunoturbidimetric assay by laboratory technicians and paediatric radiologists blinded to the clinical information.

According to study CRP concentrations could indicate which febrile children under three months of age should undergo blood culture tests during influenza seasons. If a febrile child aged 29–90 days has a CRP concentration of <5 mg/L, a routine blood culture is no longer needed for an accurate diagnosis. However, if a febrile infant of less than three months, particularly younger than 28 days, has a CRP point of >30.5 mg/L, blood cultures for an accurate diagnosis and the immediate administration of antibiotic therapy were strongly recommended. Additional conclusion of this study was that CRP provide a greater diagnostic value in identifying bacteraemia infections in febrile children of less than three months of age when compared to WBC (Total white blood cells counts) and ANC (Absolute neutrophil counts).

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